Croma PhilArt polynucleotide injections are a modern biostimulatory procedure designed for the regeneration of facial and neck skin, restoration of hydration and improvement of skin elasticity. These injections are also used to stimulate hair growth and to improve the condition of the under-eye area.
The injections contain high-technology-derived polynucleotides that are biologically compatible with human tissues.
Polynucleotides activate the skin’s natural regeneration processes:
- stimulate collagen synthesis,
- support the fibroblast life cycle,
- exhibit a strong antioxidant effect.
As a result, the skin becomes smoother, firmer, better hydrated and visibly more revitalised.
Particularly good results are achieved in the under-eye area, one of the most sensitive facial zones, where the skin is thin and prone to rapid moisture and elasticity loss.
What are polynucleotides?
Polynucleotides are natural biopolymers composed of nucleotide chains that participate in cellular renewal processes. Their structure is similar to that of human DNA, making these products well-tolerated and suitable even for sensitive areas.
PhilArt polynucleotides are derived from salmon DNA. Although the products are biologically compatible and widely used in aesthetic medicine, patients with fish or seafood allergies are always assessed individually during a medical consultation.
Polynucleotide injections do not cause long-term tissue swelling or recurrent oedema. Therefore, they can be administered to the face and under-eye area, even in patients prone to swelling or with under-eye bags.
Who are polynucleotide injections suitable for?
Polynucleotide injections are recommended for those who wish to:
- improve skin hydration balance, elasticity and tone,
- stimulate natural skin regeneration,
- reduce fine lines and uneven skin texture,
- revitalise tired, dull-looking skin,
- improve the condition of the under-eye area, reduce dark circles and puffiness, and enhance lymphatic drainage,
- stimulate scalp hair or eyebrow growth and strengthen hair follicles.
The procedure can be performed on the face, neck, décolletage, under-eye area, scalp and eyebrows.
When are polynucleotide injections not performed?
The procedure is not performed if:
- there is a known allergy to polynucleotides, fish-derived products or any of the product’s components,
- there is active inflammation or infection at the injection site (bacterial, viral, fungal infections, active herpes),
- autoimmune diseases are present, especially in the active phase,
- oncological diseases are diagnosed (active cancer or during cancer treatment),
- during pregnancy and breastfeeding,
- age is under 18 years,
- there are blood coagulation disorders (e.g. haemophilia) or anticoagulant or antiplatelet medications are used (e.g. warfarin, NOACs or high-dose aspirin),
- immunosuppressive treatment is being used,
- chronic diseases are in an exacerbation phase,
- there is a tendency to form keloid scars,
- recent aesthetic procedures have been performed (within 3 months) and recommended intervals have not yet passed (laser treatments, chemical peels, surgery),
- there is an acute viral infection (cold, flu, COVID, etc.).
Is special preparation required?
No special preparation is required. Prior to the procedure, the doctor will assess your skin condition, general health status, and allergy history, and will recommend an individualised treatment plan based on your age and health condition.
How are polynucleotide injections performed?
During the procedure, polynucleotides are injected into the dermal layer of the skin using micro-injections or micro-papules. The product begins to act immediately by activating regenerative processes in the skin.
Are polynucleotide injections painful?
Before the procedure, the treated area is numbed with a topical anaesthetic cream. As a result, micro-injections are minimally felt, and the procedure is generally well tolerated.
How long does the procedure take?
The procedure takes approximately 30–45 minutes, depending on the treated area and the extent of the procedure.
How many procedures are needed to achieve the desired result?
A standard course consists of 3–4 procedures performed every 2–3 weeks.
- For younger skin: 3 procedures every 3 weeks, with maintenance treatments every 3 months.
- For mature skin: 4 procedures every 2–3 weeks, with maintenance treatments every 3 months.
- For the under-eye area (peri-orbital biostimulation): 3 procedures every 3 weeks.
- For hair treatment: 4 procedures every 2 weeks, followed by maintenance treatments according to an individual plan.
When can results be expected, and how long do they last?
The effect is often noticeable after the first procedure: facial skin becomes smoother and more radiant. In the under-eye area, dark circles are reduced, the skin becomes more elastic and firmer, and skin tone and lymphatic drainage improve.
Optimal results are usually achieved after several weeks, once the skin has fully renewed and collagen production is fully activated.
The effects of polynucleotide injections last for approximately 6 months.
To maintain the achieved skin quality, repeat treatments are recommended; the frequency and necessity are discussed individually with the doctor.
Aftercare recommendations
- After the procedure, it is recommended to avoid covering skincare products for 24 hours.
- Make-up should not be applied on the day of the procedure.
- Intensive physical activity should be avoided for the first 48 hours.
- For 5–7 days, avoid exposure to UV radiation and visits to saunas or solariums.
- After scalp treatment, hair and injection sites should not be washed for 12 hours.
After the procedure, the treated area may appear red or swollen, and small bruises may occur. These usually resolve within one week.
Which products are used for the injections?
The PhilArt range includes:
- PhilArt for regeneration of facial, neck, décolletage and hand skin
- PhilArt Next for the neck and décolletage area
- PhilArt Eye for the under-eye area
- PhilArt Hair for the scalp, hair and eyebrows
